Human BAD activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | BAD |
| Locus ID | 572 |
| Components |
GA100391G1, BAD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100391G2, BAD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100391G3, BAD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_004322, NM_032989 |
| UniProt ID | Q92934 |
| Synonyms | BBC2; BCL2L8 |
| Summary | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. provided by RefSeq, Dec 2019 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN200634 | BAD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN200634BN | BAD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN200634LP | BAD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN200634RB | BAD - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN400634 | BAD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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