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Human ATP7B activation kit by CRISPRa

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SKU
GA100375
ATP7B CRISPRa kit - CRISPR gene activation of human ATPase copper transporting beta
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA324843 ATP7B Antibody (C-term)
400 ul
$645.00
RC223635 ATP7B (Myc-DDK-tagged)-Human ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1
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Other products for "ATP7B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATP7B
Locus ID 540
Components

GA100375G1, ATP7B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100375G2, ATP7B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100375G3, ATP7B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000053, NM_001005918, NM_001243182, NM_001330578, NM_001330579
UniProt ID P35670
Synonyms PWD; WC1; WD; WND
Summary This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. provided by RefSeq, Dec 2019
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Documents
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Other Versions
SKU Description Size Price
KN423635 ATP7B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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