Human ATP2A1 activation kit by CRISPRa

SKU
GA100342
ATP2A1 CRISPRa kit - CRISPR gene activation of human ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATP2A1
Locus ID 487
Components

GA100342G1, ATP2A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100342G2, ATP2A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100342G3, ATP2A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001286075, NM_004320, NM_173201
UniProt ID O14983
Synonyms ATP2A; SERCA1
Summary This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. provided by RefSeq, Oct 2013
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Other Versions
SKU Description Size Price
KN414911 ATP2A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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