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Human ATM activation kit by CRISPRa

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SKU
GA100329
ATM CRISPRa kit - CRISPR gene activation of human ATM serine/threonine kinase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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50 ul
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RC211894 ATM (Myc-DDK-tagged)-Human ataxia telangiectasia mutated (ATM), transcript variant 2
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Other products for "ATM"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATM
Locus ID 472
Components

GA100329G1, ATM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100329G2, ATM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100329G3, ATM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000051, NM_138292, NM_138293, NM_001351834, NM_001351835, NM_001351836
UniProt ID Q13315
Synonyms AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1
Summary The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. provided by RefSeq, Aug 2010
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Other Versions
SKU Description Size Price
KN411894 ATM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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