Human ART4 activation kit by CRISPRa

SKU GA100307

ART4 CRISPRa kit - CRISPR gene activation of human ADP-ribosyltransferase 4 (Dombrock blood group)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ART4
• Locus ID: 420
• Components:

  GA100307G1, ART4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100307G2, ART4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100307G3, ART4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021071, NM_001354646
• UniProt ID: Q93070
• Synonyms: ARTC4; CD297; DO; DOK1
• Summary: This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008]