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Human BMAL1 (ARNTL) activation kit by CRISPRa

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SKU
GA100295
ARNTL CRISPRa kit - CRISPR gene activation of human aryl hydrocarbon receptor nuclear translocator like
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA501174 Anti-ARNTL (BMAL1) mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 100 ul
$447.00
RC204464 ARNTL (Myc-DDK-tagged)-Human aryl hydrocarbon receptor nuclear translocator-like (ARNTL), transcript variant 3
10 ug
$814.00

Other products for "ARNTL"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARNTL
Locus ID 406
Components

GA100295G1, BMAL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100295G2, BMAL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100295G3, BMAL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001030272, NM_001030273, NM_001178, NM_001297719, NM_001297722, NM_001297724, NM_001351804, NM_001351805, NM_001351806, NM_001351807, NM_001351808, NM_001351809, NM_001351810, NM_001351811, NM_001351812, NM_001351813, NM_001351814, NM_001351815, NM_001351816, NM_001351817, NM_001351818, NM_001351819, NM_001351820, NM_001351821, NM_001351822, NM_001351823, NM_001351824, NR_147785, NR_147786, NR_147787, NR_147788, NR_147789, NR_147790, NR_147791
UniProt ID O00327
Synonyms bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC
Summary The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN204464 ARNTL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204464BN ARNTL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204464LP ARNTL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204464RB ARNTL - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404464 ARNTL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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