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Human Apolipoprotein H (APOH) activation kit by CRISPRa

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SKU
GA100248
APOH CRISPRa kit - CRISPR gene activation of human apolipoprotein H
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA807147 APOH mouse monoclonal antibody, clone OTI4A11 (formerly 4A11) 100 ul
$447.00
RC205017 APOH (Myc-DDK-tagged)-Human apolipoprotein H (beta-2-glycoprotein I) (APOH)
10 ug
$457.00

Other products for "APOH"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APOH
Locus ID 350
Components

GA100248G1, Apolipoprotein H gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100248G2, Apolipoprotein H gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100248G3, Apolipoprotein H gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000042
UniProt ID P02749
Synonyms B2G1; B2GP1; BG
Summary Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.provided by RefSeq, Dec 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN405017 APOH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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