Human APLP1 activation kit by CRISPRa

SKU
GA100234
APLP1 CRISPRa kit - CRISPR gene activation of human amyloid beta precursor like protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APLP1
Locus ID 333
Components

GA100234G1, APLP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100234G2, APLP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100234G3, APLP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001024807, NM_005166
UniProt ID P51693
Synonyms APLP
Summary This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402053 APLP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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