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Human ABCD2 activation kit by CRISPRa

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SKU
GA100160
ABCD2 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily D member 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA810066 ABCD2 mouse monoclonal antibody,clone OTI3B7 100 ul
$447.00
RC211199 ABCD2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2)
10 ug
$678.00

Other products for "ABCD2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ABCD2
Locus ID 225
Components

GA100160G1, ABCD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100160G2, ABCD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100160G3, ABCD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005164
UniProt ID Q9UBJ2
Synonyms ABC39; ALDL1; ALDR; ALDRP; hALDR
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN411199 ABCD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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