Human ADH6 activation kit by CRISPRa

SKU GA100089

ADH6 CRISPRa kit - CRISPR gene activation of human alcohol dehydrogenase 6 (class V)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ADH6
• Locus ID: 130
• Components:

  GA100089G1, ADH6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100089G2, ADH6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100089G3, ADH6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000672, NM_001102470, NR_132990
• UniProt ID: P28332
• Synonyms: ADH-5
• Summary: This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]