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Human ADA activation kit by CRISPRa

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SKU
GA100064
ADA CRISPRa kit - CRISPR gene activation of human adenosine deaminase
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ADA
Locus ID 100
Components

GA100064G1, ADA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100064G2, ADA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100064G3, ADA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000022, NM_001322050, NM_001322051, NR_136160
UniProt ID P00813
Synonyms adenosine aminohydrolase; adenosine deaminase
Summary This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine in the purine catabolic pathway. Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined immunodeficiency disease (SCID) which is the result of a deficiency in the ADA enzyme. In ADA-deficient individuals there is a marked depletion of T, B, and NK lymphocytes, and consequently, a lack of both humoral and cellular immunity. Conversely, elevated levels of this enzyme are associated with congenital hemolytic anemia. provided by RefSeq, Sep 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN406679 ADA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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