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TTI1 (NM_014657) Human Untagged Clone

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SKU
SC324266
TTI1 (untagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1)
  $949.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TTI1
Synonyms KIAA0406; smg-10
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_014657.1 GAGAGTGAGAGAAAGGCTGGAAGACGAGACCTGCTCACTCTGTCACCGAGGCTAGAGTAC
AGTGGCACAATCACAGCTCATTGCAGCCTCAACCTCCCAGGCTCAATCGATCCTTCCAAC
TGAGCCTCCCTAGCAGCTGGGACTATTAGTGCACACCACCACACCTAGCCTGCAGGATGT
TTCCTCAATGAGGGGAAGGCTGCTGCACAATGGCAGTTTTTGATACTCCTGAGGAGGCCT
TTGGTGTCTTACGTCCAGTCTGTGTTCAGCTCACAAAGACCCAGACAGTGGAGAATGTGG
AGCATCTGCAGACACGACTACAAGCTGTGAGTGACAGTGCCCTTCAGGAACTTCAGCAGT
ACATCCTCTTCCCTCTGCGATTTACCCTGAAGACCCCAGGTCCCAAAAGAGAGCGTTTGA
TCCAAAGTGTGGTGGAATGCCTCACATTTGTCCTTTCTTCAACATGTGTGAAAGAACAGG
AGCTTCTCCAGGAACTCTTTTCAGAACTCTCTGCTTGTCTGTATTCACCCAGCTCCCAAA
AACCTGCGGCTGTGTCCGAGGAGTTGAAATTGGCTGTGATCCAGGGACTTAGCACATTAA
TGCACTCAGCTTATGGGGACATCATTCTGACTTTTTATGAGCCCTCCATTCTGCCACGTT
TAGGATTTGCTGTATCTTTACTGTTAGGCCTTGCAGAACAGGAGAAATCAAAGCAAATTA
AAATTGCTGCCTTAAAATGTTTACAGGTTCTACTCTTGCAGTGTGATTGTCAGGACCATC
CAAGGTCATTGGATGAACTTGAACAAAAGCAGCTGGGGGATTTGTTTGCCTCTTTTTTAC
CTGGAATCTCAACTGCACTGACCAGGCTTATCACAGGAGACTTTAAACAAGGTCACAGCA
TTGTCGTATCTTCCCTAAAGATCTTTTACAAGACAGTGAGCTTCATTATGGCTGATGAAC
AGCTCAAAAGAATCTCAAAGGTCCAAGCAAAACCTGCAGTTGAGCACAGAGTAGCAGAGC
TGATGGTTTACAGGGAAGCAGATTGGGTAAAAAAGACTGGCGACAAGTTGACTATCCTTA
TTAAAAAGATAATTGAGTGTGTTTCTGTTCACCCACACTGGAAGGTGAGACTGGAACTGG
TAGAACTTGTGGAGGACCTTCTTTTGAAGTGCAGTCAATCATTGGTCGAATGTGCTGGTC
CCCTTCTGAAGGCCTTAGTGGGACTAGTAAATGATGAGAGTCCTGAAATCCAAGCCCAGT
GCAATAAAGTTCTGAGACATTTTGCAGATCAAAAAGTAGTGGTGGGCAACAAAGCCCTCG
CTGACATCTTGTCAGAAAGCCTGCATTCCCTTGCCACATCTCTTCCTCGCCTAATGAACT
CCCAAGATGACCAGGGCAAATTCTCTACTCTTTCCTTGTTACTTGGTTATCTGAAACTCT
TGGGCCCAAAAATAAACTTTGTCCTCAACTCTGTGGCCCATCTCCAGCGGCTTTCCAAAG
CACTCATCCAAGTTCTAGAGCTAGACGTGGCTGACATCAAGATTGTTGAGGAACGGCGTT
GGAACTCTGATGATCTGAATGCTTCTCCAAAGACCTCAGCCACACAGCCTTGGAACCGCA
TCCAGAGGAGATATTTCCGCTTCTTCACTGATGAGAGAATCTTCATGCTCTTGAGGCAGG
TTTGTCAGCTACTTGGTTATTATGGGAATCTTTATTTGCTTGTGGATCACTTTATGGAAC
TTTACCATCAATCTGTGGTTTACCGGAAGCAAGCTGCCATGATCCTTAATGAACTGGTTA
CAGGGGCTGCTGGGCTGGAGGTTGAGGATCTTCACGAAAAACATATTAAAACAAACCCAG
AAGAACTGAGAGAGATTGTGACATCTATACTTGAAGAATACACAAGTCAAGAAAATTGGT
ATTTGGTTACCTGTCTTGAAACTGAGGAAATGGGAGAGGAGCTGATGATGGAGCACCCAG
GCCTCCAAGCCATCACGTCTGGTGAACACACCTGCCAAGTTACATCTTTTCTAGCCTTCT
CAAAGCCAAGTCCCACTATTTGCTCCATGAACAGTAACATCTGGCAAATATGCATTCAGT
TGGAAGGAATTGGCCAGTTTGCATATGCACTAGGAAAAGACTTCTGTTTGCTCTTGATGT
CAGCCCTTTATCCAGTACTGGAGAAGGCTGGAGACCAAACCCTACTCATTAGTCAGGTGG
CTACCAGCACCATGATGGACGTTTGCCGTGCTTGTGGCTACGACTCCCTGCAGCACCTGA
TCAATCAAAATTCAGACTATTTAGTGAATGGGATCTCTTTAAATCTGCGTCATCTGGCTC
TGCATCCTCATACCCCAAAGGTCCTGGAAGTCATGCTGCGGAACTCAGATGCTAACCTGC
TTCCTTTGGTGGCAGATGTGGTTCAAGATGTCTTGGCCACCCTGGACCAATTTTACGATA
AGAGAGCTGCTTCCTTTGTCAGCGTTCTGCATGCTCTGATGGCAGCATTAGCCCAGTGGT
TCCCAGACACAGGTAATCTTGGGCACCTCCAAGAGCAAAGTTTAGGAGAAGAGGGAAGTC
ATTTGAACCAAAGACCAGCAGCTCTTGAGAAGAGCACCACCACAGCTGAAGACATCGAAC
AGTTTTTGCTGAACTACCTCAAAGAGAAGGATGTGGCAGATGGAAATGTCTCGGATTTTG
ATAATGAAGAAGAGGAACAGTCAGTCCCTCCCAAAGTGGATGAGAATGACACCCGTCCAG
ATGTGGAGCCACCACTGCCATTGCAGATCCAAATAGCCATGGACGTGATGGAACGCTGCA
TCCACTTGTTGTCAGATAAAAATCTGCAAATCCGCCTGAAGGTCTTGGATGTGCTGGATC
TGTGTGTGGTTGTTCTTCAGTCCCACAAAAACCAGCTGCTTCCCTTGGCTCATCAGGCCT
GGCCCTCGCTCGTTCACCGACTCACACGGGACGCCCCCCTGGCAGTGCTTAGAGCCTTCA
AGGTTTTACGTACCCTGGGAAGCAAGTGTGGTGACTTTCTTCGCAGCCGGTTCTGCAAAG
ATGTCCTGCCAAAGCTGGCTGGCTCCCTAGTCACCCAGGCCCCCATCAGTGCCAGGGCTG
GACCAGTTTACTCGCACACGCTGGCCTTCAAGTTGCAGCTGGCTGTCTTACAGGGCCTGG
GCCCCCTCTGTGAGAGACTGGACCTAGGTGAGGGTGACCTGAATAAAGTGGCTGATGCCT
GCTTGATTTACCTCAGTGTCAAACAGCCCGTGAAATTACAAGAGGCTGCCAGGAGCGTCT
TCCTCCACTTGATGAAGGTGGACCCAGACTCCACCTGGTTCCTCCTGAACGAGCTTTACT
GCCCCGTGCAGTTCACACCTCCCCACCCCAGCCTCCACCCTGTGCAGCTGCACGGGGCCA
GCGGGCAGCAGAACCCCTACACGACCAACGTGCTCCAGCTGCTCAAGGAGCTGCAGTGAC
CCTGCTCCCCCACCACAGAGGCCACCGATCCCTCCCCTACTGCCAGCCAGAAGCTGGGCT
GACCCCACCCCGGCCATAGGCGGTGGCAGCGGCAGCAGAGAAGGTGAATTAGTTAGCCAA
TCGATTTATAAATTGATCGATCACACAACTGCTTAGAAATGGATTGAAGGAAAGTAGCTG
ACTATTATTTATATTTCATACCTTGTGTTTTCAAGTGACATTGTCTGGTGGCTCTAAGGG
TTTAACCCCTTAGCCTACCATCTCTATAGCCCCAGCTCCCTCACAGGCCACACACACACA
CACACAAGAGGTCAGTTCCCCTCCATCTGCATACACCTCCCTGTCTTCAAATAATGAGAT
GGAACTAATTTGTTTTACCTAACCTGATCTTTGGGAAACAAACGGAAATAAAGACACTTC
TTGGATGAAAAGTAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire |
ACCN NM_014657
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014657.1, NP_055472.1
RefSeq Size 3931 bp
RefSeq ORF 3270 bp
Locus ID 9675
UniProt ID O43156
Cytogenetics 20q11.23
Summary Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform.
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Documents
Resources
"NM_014657" in other vectors (7)
SKU Description Size Price
RC201622 TTI1 (Myc-DDK-tagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) 10 ug
$948.00
RC201622L1 Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), Myc-DDK-tagged 10 ug
$1,248.00
RC201622L2 Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), mGFP tagged 10 ug
$1,248.00
RC201622L3 Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), Myc-DDK-tagged 10 ug
$1,248.00
RC201622L4 Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), mGFP tagged 10 ug
$1,248.00
RG201622 TTI1 (tGFP-tagged) - Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) 10 ug
$789.00 $1,148.00
SC100424 TTI1 (untagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) 10 ug
$949.00

file-alt Citations

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