RBFOX2 (NM_001031695) Human Untagged Clone

SKU SC320568

RBFOX2 (untagged)-Human RNA binding protein, fox-1 homolog (C. elegans) 2 (RBFOX2), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: RBFOX2
• Synonyms: dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBM9; RTA
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001031695.2 CTGCCAGAGAGGAAGAGAAAAGAAAGGAAGAAACATTAGAAAGAAAAAGGAAGGAAAACG; GTATAAAGAGAGATCAATTACCCACCCTTAAATAGCTAGATTGGGGGGGAGGGGGGTGGA; AAAGAAAGCTGTGGAGGTGTGCCCCAGCACGGCTGCTTTGAAAGGTTTATCATCTATCCG; TTTGGTTTATGGAGAAAAAGAAAATGGTAACTCAGGGTAACCAGGAGCCGACAACAACTC; CTGACGCAATGGTTCAGCCTTTTACTACCATCCCATTTCCACCACCTCCGCAGAATGGAA; TTCCCACAGAGTATGGGGTGCCACACACTCAAGACTATGCCGGCCAGACCGGTGAGCATA; ACCTGACACTCTACGGAAGTACGCAAGCCCACGGGGAGCAGAGCAGCAACTCACCCAGCA; CACAAAATGGATCTCTTACGACAGAAGGTGGAGCACAGACAGACGGCCAGCAGTCACAGA; CACAAAGTAGTGAAAATTCAGAGAGTAAATCTACCCCGAAACGGCTGCATGTCTCTAATA; TTCCTTTCCGCTTCCGGGACCCTGACCTCCGGCAGATGTTTGGGCAGTTTGGCAAAATCC; TAGATGTAGAAATAATCTTTAATGAACGTGGCTCTAAGGGATTCGGGTTCGTAACTTTCG; AGAATAGTGCTGATGCAGACAGGGCCAGGGAGAAATTACACGGCACCGTGGTAGAGGGCC; GTAAAATCGAGGTGAATAATGCTACAGCACGTGTAATGACCAATAAGAAGATGGTCACAC; CATATGCAAATGGTTGGAAATTAAGCCCAGTAGTTGGAGCTGTATATGGTCCGGAGTTAT; ATGCAGCATCCAGCTTTCAAGCAGATGTGTCCCTAGGCAATGATGCAGCAGTGCCCCTAT; CAGGAAGAGGGGGTATCAACACTTACATTCCTTTAATCAGTCTCCCTTTAGTTCCTGGCT; TCCCTTACCCTACTGCAGCCACCACGGCAGCCGCTTTCAGAGGAGCCCATTTGAGGGGCA; GAGGGCGGACAGTATATGGTGCAGTCCGAGCGGTACCTCCAACAGCCATCCCCGCCTATC; CAGGTGTGGTTTACCAGGACGGATTTTACGGTGCTGACCTCTATGGTGGATATGCAGCCT; ACAGATATGCACAGCCTGCTACTGCAACCGCAGCCACCGCTGCTGCAGCCGCTGCAGCCG; CTTACAGTGACGGTTATGGCAGGGTGTACACAGCCGACCCCTACCATGCCCTTGCCCCTG; CCGCTAGCTATGGAGTTGGCGCTGTGGCGAGTTTATACCGAGGTGGCTACAGCCGATTTG; CCCCCTACTGAAGTGACGTGAGACCCCTGCAAATGGGACAGCCCCCCAGTTCACGAGGCC; TGGCTATTGCAATATTTACTAGTAGAGGAACTCTATAGCAAGATGAAGAGGAAAAACAAA; CAAACAAACAAAAAAAAACACAAAAAAAGAAAGAATACTTTTTTATACCTCACTATGTTC; TTTGAATATGTATTTTTCCTTTAAATTTCTGCCTTTAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001031695
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001031695.2, NP_001026865.1
• RefSeq Size: 6997 bp
• RefSeq ORF: 1143 bp
• Locus ID: 23543
• UniProt ID: O43251
• Cytogenetics: 22q12.3
• Protein Families: Druggable Genome, Transcription Factors
• Summary: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.