SOX13 (NM_005686) Human Tagged ORF Clone
$579.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | SOX13 |
| Synonyms | ICA12; Sox-13 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_005686 |
| ORF Size | 1866 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_005686.3 |
| RefSeq Size | 4088 bp |
| RefSeq ORF | 1869 bp |
| Locus ID | 9580 |
| UniProt ID | Q9UN79 |
| Cytogenetics | 1q32.1 |
| Protein Families | Transcription Factors |
| MW | 69 kDa |
| Summary | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_005686" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC210697L1 | Lenti ORF clone of Human SRY (sex determining region Y)-box 13 (SOX13), Myc-DDK-tagged | 10 ug |
$879.00
|
|
| RC210697L2 | Lenti ORF clone of Human SRY (sex determining region Y)-box 13 (SOX13), mGFP tagged | 10 ug |
$879.00
|
|
| RC210697L3 | Lenti ORF clone of Human SRY (sex determining region Y)-box 13 (SOX13), Myc-DDK-tagged | 10 ug |
$879.00
|
|
| RC210697L4 | Lenti ORF clone of Human SRY (sex determining region Y)-box 13 (SOX13), mGFP tagged | 10 ug |
$879.00
|
|
| RG210697 | SOX13 (tGFP-tagged) - Human SRY (sex determining region Y)-box 13 (SOX13) | 10 ug |
$489.00
$779.00
|
|
| SC322778 | SOX13 (untagged)-Human SRY (sex determining region Y)-box 13 (SOX13) | 10 ug |
$580.00
|
|
Citations
Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells
Demos, Johnson, Andueza et al
Front Cardiovasc Med (2022) 9, 979745 DOI: 10.3389/fcvm.2022.979745
Demos, Johnson, Andueza et al
Front Cardiovasc Med (2022) 9, 979745 DOI: 10.3389/fcvm.2022.979745
Cited by 19
AI Summary: OriGene’s SOX13-myc-DDK-tagged plasmid (RC210697) was used in this study to overexpress SOX13 in endothelial cells, enabling the researchers to investigate SOX13’s role in repressing pro-inflammatory chemokine expression and preventing endothelial inflammation.
Snippet: d at a final concentration of 50nM to achieve a robust knockdown. For plasmid transfections, Lipofectamine 3000 (Thermo Fisher Scientific 15338030) was used as we reported (13). SOX13-myc-DDK-tagged (Origene RC210697) was used with a GFP- or RFP-(for monocyte adhesion assay) expressing plasmid with the same backbone as a control (pCMV backbone from Addgene #11153). MetCCL5 (R&D 335-RM-025) was add
Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis
Brunmeir, Wu, Peng et al
PLoS Genet. (2016) 12 (12), e1006474 DOI: 10.1371/journal.pgen.1006474
Brunmeir, Wu, Peng et al
PLoS Genet. (2016) 12 (12), e1006474 DOI: 10.1371/journal.pgen.1006474
AI Summary: OriGene products contributed to this study by providing plasmids containing full-length cDNAs for hSix1 (RC203465), hSox13 (RC210697), hPim1 (RC205853), mEbf2 (MR224591), and a lenti-viral vector with EF1a promoter and C-terminal tGFP-tag (PS100072), which were used for gene expression and functional validation experiments in brown adipogenesis.
Snippet: Plasmids containing full length cDNA were purchased from OriGene (hSix1 (RC203465), hSox13 (RC210697), hPim1 (RC205853), mEbf2 (MR224591)) or Addgene (hRreb1 (41145)), and sub-cloned into a lenti-viral vector providing an EF1a promoter for expression and a C-terminal tGFP-tag (OriGene PS100072)
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
