STAT4 (NM_003151) Human Tagged ORF Clone
SKU
RC206892
STAT4 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 4 (STAT4)
$685.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | STAT4 |
| Synonyms | SLEB11 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_003151 |
| ORF Size | 2244 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_003151.4 |
| RefSeq Size | 2840 bp |
| RefSeq ORF | 2247 bp |
| Locus ID | 6775 |
| UniProt ID | Q14765 |
| Cytogenetics | 2q32.2-q32.3 |
| Domains | SH2, STAT |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway |
| MW | 85.9 kDa |
| Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Aug 2011 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_003151" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC206892L1 | Lenti ORF clone of Human signal transducer and activator of transcription 4 (STAT4), Myc-DDK-tagged | 10 ug |
$985.00
|
|
| RC206892L2 | Lenti ORF clone of Human signal transducer and activator of transcription 4 (STAT4), mGFP tagged | 10 ug |
$985.00
|
|
| RC206892L3 | Lenti ORF clone of Human signal transducer and activator of transcription 4 (STAT4), Myc-DDK-tagged | 10 ug |
$985.00
|
|
| RC206892L4 | Lenti ORF clone of Human signal transducer and activator of transcription 4 (STAT4), mGFP tagged | 10 ug |
$985.00
|
|
| RG206892 | STAT4 (tGFP-tagged) - Human signal transducer and activator of transcription 4 (STAT4) | 10 ug |
$789.00
$885.00
|
|
| SC118193 | STAT4 (untagged)-Human signal transducer and activator of transcription 4 (STAT4) | 10 ug |
$686.00
|
|
Citations
STAT4 mediated modulation of T-B cell interactions profiling: enhances antitumor immunity in non-small cell lung cancer (NSCLC)
Bibi, George, Sarkar
Mol Biol Rep (2026) 53 (1), 389 DOI: 10.1007/s11033-026-11558-8
Bibi, George, Sarkar
Mol Biol Rep (2026) 53 (1), 389 DOI: 10.1007/s11033-026-11558-8
Paracoccidioidomycosis associated with a heterozygous STAT4 mutation and impaired IFN-γ immunity
Schimke, Hibbard, Martinez-Barricarte et al
J. Infect. Dis. (2017)
Schimke, Hibbard, Martinez-Barricarte et al
J. Infect. Dis. (2017)
AI Summary: OriGene's pCMV6 plasmids containing wild-type and mutant STAT4 were used to transfect HEK293T cells, enabling the researchers to assess the effects of STAT4 mutations on protein expression and function in this study.
Snippet: For that, HEK293T cells were transfected with 10μg of pCMV6 plasmid (OriGene, Beijing, China) containing WT, E651V or Y693W/S721T STAT4 and total STAT4 expression assessed by western blot (rabbit anti-STAT4, Cell Signaling Technology). ...;... For that, HEK293T cells were transfected with 10μg of pCMV6 plasmid (OriGene, Beijing, China) containing WT, E651V or Y693W/S721T STAT4 and total STAT4 expression assessed by western blot (rabbit anti-STAT4, Cell Signaling Technology).
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
