Foxo4 (NM_018789) Mouse Tagged ORF Clone
$289.00
$471.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Foxo4 |
| Synonyms | afx; Afxh; Mllt7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_018789 |
| ORF Size | 1515 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_018789.2, NP_061259.1 |
| RefSeq Size | 3162 bp |
| RefSeq ORF | 1518 bp |
| Locus ID | 54601 |
| UniProt ID | Q9WVH3, B1AUT3 |
| Cytogenetics | X 43.89 cM |
| MW | 53.6 kDa |
| Summary | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity). Represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_018789" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC217164 | Foxo4 (untagged) - Mouse forkhead box O4 (Foxo4), (10ug) | 10 ug |
$518.00
|
|
| MG222345 | Foxo4 (tGFP-tagged) - Mouse forkhead box O4 (Foxo4), (10ug) | 10 ug |
$489.00
$671.00
|
|
| MR222345L3 | Lenti ORF clone of Foxo4 (Myc-DDK-tagged) - Mouse forkhead box O4 (Foxo4) | 10 ug |
$771.00
|
|
| MR222345L4 | Lenti ORF clone of Foxo4 (mGFP-tagged) - Mouse forkhead box O4 (Foxo4) | 10 ug |
$771.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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