Foxo4 (NM_018789) Mouse Untagged Clone

SKU
MC217164
Foxo4 (untagged) - Mouse forkhead box O4 (Foxo4), (10ug)
  $518.00
4 Weeks*
Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Foxo4
Synonyms afx; Afxh; Mllt7
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC217164 representing NM_018789
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGATCCAGAGAATAAGAAGTCAGCCACAGGGGCTGCCGCGATCCTAGACCTCGATCCCGACTTCGAAC
CCCAGAGCCGTCCGCGATCCTGCACCTGGCCCCTTCCTCGACCAGACCTCGCTACGGAGCCACACGAACC
GTCCGAGGTGGAGCCCAGTCTGGGACAGAAGGTACCCACGGAGGGACACTCCGAACCGATCCTGTTGCCC
TCTCGGCTCCCAGAGCCGGCAGGGGGCCCCCAGCCGGGAATCCTGGGGGCTGTAACAGGTCCTCGGAAGG
GAGGCTCCCGCCGGAATGCCTGGGGAAATCAGTCATATGCAGAACTCATCAGCCAGGCCATTGAAAGCGC
CCCGGAGAAGCGGCTGACACTCGCCCAGATCTACGAATGGATGGTCCGCACGGTGCCCTACTTCAAGGAC
AAGGGTGACAGCAACAGCTCGGCAGGATGGAAGAACTCCATCCGTCACAACCTGTCCTTGCACAGCAAGT
TCATCAAGGTTCACAACGAGGCCACTGGCAAGAGCTCTTGGTGGATGCTGAACCCCGATGGCGGCAAGGG
TGGCAAGGCACCCCGCCGCAGGGCTGCCTCCATGGATAGCAGCAGCAAGCTGCTCCGGGGCCGCAGCAAA
GGCCCCAAGAAGAAGCCGTCTGTCCTGCCAGCTCCACCGGAAGGTGCCACGCCAAGGAGCCCTCTGGGCC
ACTTTGCCAAGTGGTCAAGCAGCCCTTGTCCTCGAAATCGAGAAGAAGCTGATGTGTGGACCACTTTCCG
TCCACGAAGCAGTTCAAATGCTAGCACCGTCAGCACCCGGCTGTCGCCAATGAGGCCGGAGTCTGAAGTG
CTAGCAGAAGAGGAAATGCCAGCCTCGGCCAGCAGCTATGCAGGGGGGGTCCCTCCCACGCTCAGTGAAG
ATCTAGAGCTACTGGATGGGCTCAATCTCGCATCTCCCCATTCCTTGCTCTCTAGGAGCGGTCTCTCCGG
CTTCTCTTTGCAGCATCCTGGGCTTGCTGGCCCCTTACATAGCTATGGTGCCTCCCTCTTTGGCCCAATA
GATGGGTCTTTGTCAGCAGGAGAAGGGTGCTTCTCAAGTTCCCAGTCTCTAGAGGCTCTGCTCACCTCTG
ATACACCACCACCTCCTGCTGATGTCCTCATGACCCAGGTAGATCCTATCCTGTCTCAGGCTCCTACACT
TCTGTTACTGGGAGGAATGCCTTCCTCTAGCAAGCTGGGCACAGGAGTCAGCCTGTGTCCTACGCCGCTA
GAGGGTCCTGGTCCCAGCAACCTGGTCCCCAACCTTTCTGTGATGGCACCACCCCCAGTCATGGCAGGCG
CTCCCATCCCTAAGGTCCTGGGAACCCCTGTGCTCGCATCTCCTACTGAAGATTCCAGCCATGACAGAAT
GCCTCAGGATCTGGATCTTGATATGTATATGGAGAACCTGGAGTGCGACATGGATAACATCATCAGTGAC
CTCATGGATGGTGAGGGACTGGACTTCAACTTTGAGCCAGATCCCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_018789
Insert Size 1518 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_018789.2, NP_061259.1
RefSeq Size 3162 bp
RefSeq ORF 1518 bp
Locus ID 54601
UniProt ID Q9WVH3
Cytogenetics X 43.89 cM
Summary Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity). Represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_018789" in other vectors (4)
SKU Description Size Price
MG222345 Foxo4 (tGFP-tagged) - Mouse forkhead box O4 (Foxo4), (10ug) 10 ug
$489.00 $671.00
MR222345 Foxo4 (Myc-DDK-tagged) - Mouse forkhead box O4 (Foxo4) 10 ug
$289.00 $471.00
MR222345L3 Lenti ORF clone of Foxo4 (Myc-DDK-tagged) - Mouse forkhead box O4 (Foxo4) 10 ug
$771.00
MR222345L4 Lenti ORF clone of Foxo4 (mGFP-tagged) - Mouse forkhead box O4 (Foxo4) 10 ug
$771.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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