Ppp6c (NM_024209) Mouse Tagged ORF Clone
- TrueORF®
SKU
MR204292
Ppp6c (Myc-DDK-tagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c)
$289.00
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Ppp6c |
| Synonyms | 2310003C10Rik; Pp6C |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_024209 |
| ORF Size | 915 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_024209.3 |
| RefSeq Size | 1583 bp |
| RefSeq ORF | 918 bp |
| Locus ID | 67857 |
| UniProt ID | Q9CQR6 |
| Cytogenetics | 2 B |
| MW | 35.2 kDa |
| Summary | Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential step that triggers RIG-I/DDX58-mediated signaling activation.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_024209" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC207641 | Ppp6c (untagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c), (10ug) | 10 ug |
$330.00
|
|
| MG204292 | Ppp6c (tGFP-tagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c) | 10 ug |
$500.00
|
|
| MR204292L3 | Lenti ORF clone of Ppp6c (Myc-DDK-tagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c) | 10 ug |
$600.00
|
|
| MR204292L4 | Lenti ORF clone of Ppp6c (mGFP-tagged) - Mouse protein phosphatase 6, catalytic subunit (Ppp6c) | 10 ug |
$600.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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