Rab5a (NM_025887) Mouse Untagged Clone
$330.00
4 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Rab5a |
| Synonyms | 2410015H04Rik; AI663973; AU021172; nnyRab5a |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_025887 |
| Insert Size | 648 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_025887.4, NP_080163.1 |
| RefSeq Size | 2364 bp |
| RefSeq ORF | 648 bp |
| Locus ID | 271457 |
| UniProt ID | Q9CQD1 |
| Cytogenetics | 17 27.82 cM |
| Summary | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (By similarity). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (PubMed:18425118).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_025887" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG202355 | Rab5a (tGFP-tagged) - Mouse RAB5A, member RAS oncogene family (Rab5a) | 10 ug |
$489.00
$500.00
|
|
| MR202355 | Rab5a (Myc-DDK-tagged) - Mouse RAB5A, member RAS oncogene family (Rab5a) | 10 ug |
$289.00
$300.00
|
|
| MR202355L3 | Lenti ORF clone of Rab5a (Myc-DDK-tagged) - Mouse RAB5A, member RAS oncogene family (Rab5a) | 10 ug |
$600.00
|
|
| MR202355L4 | Lenti ORF clone of Rab5a (mGFP-tagged) - Mouse RAB5A, member RAS oncogene family (Rab5a) | 10 ug |
$600.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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