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TissueScan, Ovarian Cancer cDNA Array II

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SKU
HORT502
TissueScan Ovarian Cancer Tissue qPCR Panel II (10) containing ten identical sets of 48 tissues covering four disease stages and normal tissues
  $2,500.00
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Specifications
Specifications
Product Data
TissueScan Type Cancer Specific
Array Name Ovarian Cancer cDNA Array II
Clinical Info
Diagnosis Category Ovarian Cancer
Tissue Ovary
Shipping Ambient
Description TissueScan Ovarian Cancer Tissue qPCR Panel II (10) containing ten identical sets of 48 tissues covering four disease stages and normal tissues
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Mitochondrial and cytosolic one-carbon metabolism is a targetable metabolic vulnerability in cisplatin-resistant ovarian cancer
Wallace-Povirk, O'Connor, Dekhne et al
Mol Cancer Ther (2024)
AI Summary: OriGene contributed HORT502 lyophilized cDNAs from primary epithelial ovarian cancer specimens and normal ovaries, which were used for gene expression analysis in this study.
Snippet: Forty-eight lyophilized cDNAs from primary EOC specimens (8 stage I, 9 stage II, 17 stage III, and 6 stage IV) and 8 cDNAs from normal ovaries (Supplemental Table S1) were purchased from Origene (HORT502). RNAs were isolated from EOC cell lines (TRIzol;Life Technologies). cDNAs were synthesized with random hexamers and MuLV reverse transcriptase and purified (QIAquick PCR Purification Kit, Qiagen). …
Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment
Wallace-Povirk, Rubinsak, Malysa et al
Sci Rep (2022) 12 (1), 11346 DOI: 10.1038/s41598-022-14788-5
Cited by 15
AI Summary: OriGene’s cDNA samples from normal ovary and high-grade serous ovarian cancer (HGSOC) were used to measure transcript levels of GARFTase and AICARFTase, enabling comparison of gene expression between primary tissues and cell lines in this study.
Snippet: samples and BR-5 and BR-Luc cells. Transcript levels for GARFTase (A) and AICARFTase (B) were measured using cDNAs from primary specimens including normal ovary (n = 8) and HGSOC (n = 39) (OriGene) and results were compared to those for EOC cell lines including IGROV1, SKOV3, A2780 and A2780 E-80. Transcript levels were normalized to β-actin transcripts. Statistical analyses were perfo;- levels ...
FigureFigureFigure
Changes in SLIT2 expression are associated with the migration of human ovarian clear cell carcinoma cells
Lin, Huang, Wu et al
Oncol Lett (2021) 22 (1), 551 DOI: 10.3892/ol.2021.12812
Cited by 10
AI Summary: In this study, OriGene products—specifically, the SLIT2 human cDNA ORF clone and SLIT2 siRNA—were used to overexpress and knock down SLIT2 in ovarian clear cell carcinoma cells, enabling the researchers to demonstrate SLIT2’s role in regulating cancer cell migration.
FigureFigureFigure
Changes in SLIT2 expression are associated with the migration of human ovarian clear cell carcinoma cells
Lin, Huang, Wu et al
Oncol Lett (2021) 22 (1) DOI: 10.3892/ol.2021.12812
Cited by 10
AI Summary: OriGene’s Human Ovary Total RNA (HORT502) and Human Ovary Tumor Total RNA (HORT504) products were used to assess SLIT2 mRNA expression in normal and ovarian tumor tissue samples in this study.
Snippet: nos. HORT502 and HORT504;OriGene Technologies, Inc.) were purchased on 4 April, 2018, to examine the mRNA expression levels of SLIT2 in cDNA samples that had been prepared from normal ovarian and ovarian tumor tissue samples
PRSS21/testisin inhibits ovarian tumor metastasis and antagonizes proangiogenic angiopoietins ANG2 and ANGPTL4
Conway, Buzza, Martin et al
J. Mol. Med. (2019) 97 (5), 691-709 DOI: 10.1007/s00109-019-01763-3
AI Summary: OriGene’s TissueScan Ovarian Cancer cDNA Array II (HORT502) was used in this study to screen and analyze testisin and PAR-2 mRNA expression across different stages and types of ovarian cancer, aiding the investigation of gene expression patterns relevant to tumor progression and metastasis.
Snippet: The TissueScan Ovarian Cancer cDNA Array II (II (HORT502;Origene) containing 48 samples covering four disease stages of varying histopathologies, and normal tissues were screened for testisin and PAR-2 mRNA gene expression using TaqMan Master Mix and
Showing 1-5 of 5 papers.
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