TIE2 (TEK) Human shRNA Plasmid Kit (Locus ID 7010)

SKU
TG320546
TEK - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 7010
Synonyms CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components TEK - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 7010). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_000459, NM_001290077, NM_001290078, NM_000459.1, NM_000459.2, NM_000459.3, NM_000459.4, NM_001290078.1, NM_001290077.1, BC035514, BC035514.1, NM_000459.5
UniProt ID Q02763
Summary This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. provided by RefSeq, Feb 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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