TIE2 (TEK) Rabbit Polyclonal Antibody

SKU
TA323651
Anti-TEK Rabbit Polyclonal Antibody
  $305.00
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 516-529 amino acids of human TEK tyrosine kinase, endothelial
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name TEK receptor tyrosine kinase
Database Link
Background The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice; rats; and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Synonyms CD202B; TIE-2; TIE2; VMCM; VMCM1
Reference Data
Protein Categories CD Markers, Enzyme: Kinases, Growth Factors, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
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Documents
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file-alt Citations

Development and external validation of a composite immune-clinical prognostic model associated with EGFR mutation in East-Asian patients with lung adenocarcinoma
Liu, Zheng, Wang et al
Ther Adv Med Oncol (2021) 13, 17588359211006949 DOI: 10.1177/17588359211006949
Cited by 8
AI Summary: OriGene contributed to this study by providing the anti-human ANGPT4 rabbit recombinant polyclonal antibody (TA350852), which was used for immunohistochemical assessment of ANGPT4 protein expression as part of validating the prognostic model in lung adenocarcinoma patients.
Snippet: of the selected 10 EIGs in the CICAMS cohort. Expression of 10 genes were assessed with IHC using an angiopoietin 4 (ANGPT4) assay (anti-human ANGPT4 rabbit recombinant polyclonal antibody, TA350852;OriGene, USA), a brain-derived neurotrophic factor (BDNF) assay (anti-human BDNF rabbit recombinant monoclonal antibody, ab108319;Abcam, USA), a fatty acid binding protein 7 (FABP7) assay (anti-human
FigureFigureFigure
IHC
Showing 1-1 of 1 papers.
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