BDNF (NM_001709) Human Recombinant Protein

SKU
TP762592
Purified recombinant protein of Human brain-derived neurotrophic factor (BDNF), transcript variant 4, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region full length of BDNF
Tag N-GST and C-HIS
Predicted MW 27.82 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001700
Locus ID 627
UniProt ID P23560 A0A0E3SU01
Cytogenetics 11p14.1
RefSeq Size 3972
RefSeq ORF 741
Synonyms ANON2; BULN2
Summary This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. provided by RefSeq, Nov 2015
Protein Categories Growth Factors, Membrane Proteins, Secreated Proteins
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane
Protein Pathways Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway
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LY428351 Transient overexpression lysate of brain-derived neurotrophic factor (BDNF), transcript variant 7 (as WB positive control) 100 ug
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LY428355 Transient overexpression lysate of brain-derived neurotrophic factor (BDNF), transcript variant 17 (as WB positive control) 100 ug
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LY428357 Transient overexpression lysate of brain-derived neurotrophic factor (BDNF), transcript variant 11 (as WB positive control) 100 ug
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LY428358 Transient overexpression lysate of brain-derived neurotrophic factor (BDNF), transcript variant 12 (as WB positive control) 100 ug
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