CD22 (NM_001771) Human Recombinant Protein
SKU
TP762390
Purified recombinant protein of Human CD22 molecule (CD22), transcript variant 1, Asp20-Ala330, with N-terminal His tag, expressed in E.coli, 50ug
$260.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-His |
| Predicted MW | 35.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | >80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001762 |
| Locus ID | 933 |
| UniProt ID | P20273 |
| Cytogenetics | 19q13.12 |
| RefSeq Size | 3300 |
| RefSeq ORF | 2541 |
| Synonyms | SIGLEC-2; SIGLEC2 |
| Summary | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.UniProtKB/Swiss-Prot Function |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
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|---|---|---|---|---|
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| LC434364 | Lyophilized CD22 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
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| LY434364 | Transient overexpression lysate of CD22 molecule (CD22), transcript variant 4 (as WB positive control) | 100 ug |
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| TP721302 | Human CD22 Protein (C-His) | 25 ug |
$300.00
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| TP721303 | Human CD22 Protein (C-His-Avi) | 25 ug |
$300.00
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|
| TP721304 | Biotinylated Human CD22 Protein (C-His-Avi) | 25 ug |
$430.00
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| TP721305 | PE Conjugated Human CD22 Protein (C-His) | 25 ug |
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| TP721306 | APC Conjugated Human CD22 Protein (C-His) | 25 ug |
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| TP721307 | Human CD22 Protein (C-Fc) | 25 ug |
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|
| TP723928 | Recombinant human CD22 protein with C-terminal human Fc and 6×His tag | 100 ug |
$795.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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