OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

CD22 Human Recombinant Protein

Be the first to review this product
SKU
TP723928
Recombinant human CD22 protein with C-terminal human Fc and 6×His tag
Size:
100 ug
  $795.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA506407 CD22 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12) 100 ul
$447.00

Other products for "CD22"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD22(Asp20-Arg687) hFc(Glu99-Ala330) 6×His tag
Tag C-Human Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 102.1 kDa after removal of the signal peptide. The apparent molecular mass of CD22-hFc-His is approximately 130-180 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 933
UniProt ID P20273
Synonyms CD22;SIGLEC2;BL-CAM;SIGLEC-2;Siglec2;SIGLEC2FLJ22814
Summary B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "CD22" proteins (11)
SKU Description Size Price
PH316939 CD22 MS Standard C13 and N15-labeled recombinant protein (NP_001762) 10 ug
$3,360.00
LC434364 Lyophilized CD22 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY434364 Transient overexpression lysate of CD22 molecule (CD22), transcript variant 4 (as WB positive control) 100 ug
$665.00
TP316939 Recombinant protein of human CD22 molecule (CD22), 20 µg 20 ug
$737.00
TP721302 Human CD22 Protein (C-His) 25 ug
$300.00
TP721303 Human CD22 Protein (C-His-Avi) 25 ug
$300.00
TP721304 Biotinylated Human CD22 Protein (C-His-Avi) 25 ug
$430.00
TP721305 PE Conjugated Human CD22 Protein (C-His) 25 ug
$430.00
TP721306 APC Conjugated Human CD22 Protein (C-His) 25 ug
$430.00
TP721307 Human CD22 Protein (C-Fc) 25 ug
$300.00
TP762390 Purified recombinant protein of Human CD22 molecule (CD22), transcript variant 1, Asp20-Ala330, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$260.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products