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SIRP alpha (SIRPA) (NM_001040022) Human Recombinant Protein

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SKU
TP762372
Purified recombinant protein of Human signal-regulatory protein alpha (SIRPA), transcript variant 1, Glu31-Ile373, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Glu31-Ile373) of SIRPA
Tag N-His
Predicted MW 37.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
Locus ID 140885
UniProt ID P78324
Cytogenetics 20p13
RefSeq Size 4201
RefSeq ORF 1515
Synonyms BIT; CD172A; MFR; MYD-1; P84; PTPNS1; SHPS1; SIRP
Summary The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. provided by RefSeq, Jul 2008
Protein Categories CD Markers, Chemokines, Cytokines, Growth Factors, Membrane Proteins
Protein Families Druggable Genome, Phosphatase, Transmembrane
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Other "SIRP alpha" proteins (13)
SKU Description Size Price
PH307315 SIRPA MS Standard C13 and N15-labeled recombinant protein (NP_542970) 10 ug
$3,360.00
PH316320 SIRPA MS Standard C13 and N15-labeled recombinant protein (NP_001035112) 10 ug
$3,360.00
PH322380 SIRPA MS Standard C13 and N15-labeled recombinant protein (NP_001035111) 10 ug
$3,360.00
LC409074 Lyophilized SIRPA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421878 Lyophilized SIRPA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421879 Lyophilized SIRPA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY409074 Transient overexpression lysate of signal-regulatory protein alpha (SIRPA), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY421878 Transient overexpression lysate of signal-regulatory protein alpha (SIRPA), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY421879 Transient overexpression lysate of signal-regulatory protein alpha (SIRPA), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP307315 Recombinant protein of human signal-regulatory protein alpha (SIRPA), transcript variant 3, 20 µg 20 ug
$737.00
TP316320 Recombinant protein of human signal-regulatory protein alpha (SIRPA), transcript variant 2, 20 µg 20 ug
$737.00
TP322380 Recombinant protein of human signal-regulatory protein alpha (SIRPA), transcript variant 1, 20 µg 20 ug
$737.00
TP723932 Recombinant Human SIRPa with C-terminal human Fc and 6×His tag 100 ug
$795.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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