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EMA (MUC1) (NM_001018017) Human Recombinant Protein

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SKU
TP760771
Purified recombinant protein of Human mucin 1, cell surface associated (MUC1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length MUC1
Tag N-His
Predicted MW 25.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001018017
Locus ID 4582
UniProt ID P15941
Cytogenetics 1q22
RefSeq Size 1166
RefSeq ORF 765
Synonyms ADMCKD; ADMCKD1; ADTKD2; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
Summary This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.provided by RefSeq, Feb 2011
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
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Documents
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Other "EMA" proteins (10)
SKU Description Size Price
PH321390 MUC1 MS Standard C13 and N15-labeled recombinant protein (NP_001018016) 10 ug
$3,360.00
LC400880 Lyophilized MUC1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC420828 Lyophilized MUC1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422694 Lyophilized MUC1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422695 Lyophilized MUC1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400880 Transient overexpression lysate of mucin 1, cell surface associated (MUC1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY420828 Transient overexpression lysate of mucin 1, cell surface associated (MUC1), transcript variant 6 (as WB positive control) 100 ug
$436.00
LY422694 Transient overexpression lysate of mucin 1, cell surface associated (MUC1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY422695 Transient overexpression lysate of mucin 1, cell surface associated (MUC1), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP321390 Recombinant protein of human mucin 1, cell surface associated (MUC1), transcript variant 2, 20 µg 20 ug
$737.00

file-alt Citations

Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins
Ahn, Kamath, Mohamedali et al
J Proteome Res (2021)
Cited by 25
AI Summary: In this study, OriGene products TIMP2 (TP723886) and TNFRSF1A (TP723870) were used as recombinant proteins to construct a spectral library, which enabled improved detection of low abundance cancer-associated plasma proteins by mass spectrometry.
Snippet: Credible detection and quantification of low abundance proteins from human blood plasma is a major challenge in precision medicine biomarker discovery when using mass spectrometry (MS). In this pro...;TIMP2 (TP723886) andTNFRSF1A (TP723870) were purchased from OriGeneTechnologies, CEACAM5 (4128-CM), CST3 (1196-PI),
Showing 1-1 of 1 papers.
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