EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: OTI2F6]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2F6 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 25.1 kDa |
| Gene Name | mucin 1, cell surface associated |
| Database Link | |
| Background | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. provided by RefSeq, Feb 2011 |
| Synonyms | ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; SEC |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Reviews
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Resources
Other "OTI2F6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF800790 | Carrier-free (BSA/glycerol-free) MUC1 mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) | 100 ug |
$620.00
|
|
| TA800790AM | MUC1 mouse monoclonal antibody,clone 2F6, Biotinylated | 100 ul |
$509.00
|
|
| TA800790BM | MUC1 mouse monoclonal antibody,clone 2F6, HRP conjugated | 100 ul |
$509.00
|
|
| TA800790S | MUC1 (EMA) mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) | 30 ul |
$200.00
|
|
Citations
Clinicopathological Characteristics of Pseudomyxoma Peritonei Originated from Ovaries
Yan, Shi, Li et al
Cancer Manag Res (2020) 12, 7569-7578 DOI: 10.2147/CMAR.S264474
Yan, Shi, Li et al
Cancer Manag Res (2020) 12, 7569-7578 DOI: 10.2147/CMAR.S264474
AI Summary: OriGene products, specifically anti-SATB2 antibody (TA806083) and anti-Villin antibody (TA500492), were used for immunohistochemical staining to help characterize and differentiate ovarian-origin pseudomyxoma peritonei tumors in this study.
Showing 1-1 of 1 papers.
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