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PD-L1 (CD274) Human Recombinant Protein

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SKU
TP724015
Recombinant human PD-L1 protein with C-terminal 6×His tag
Size:
100 ug
  $700.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (2)

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Other products for "PD-L1"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
PD-L1(Phe19-Arg238) 6×His tag
Tag C-6×His Tag
Predicted MW The protein has a predicted molecular mass of 26.0 kDa after removal of the signal peptide.The apparent molecular mass of PDL1-His is approximately 33-35 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 29126
UniProt ID Q9NZQ7
Synonyms PD-L1;CD274;B7-H1;PDCD1L1;PDCD1LG1
Summary This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Cytokines, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
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Other "PD-L1" proteins (19)
SKU Description Size Price
LC415473 Lyophilized CD274 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415473 Transient overexpression lysate of PD-L1 / CD274 molecule (PD-L1 / CD274) (as WB positive control) 100 ug
$436.00
TP700200 Purified recombinant protein of Homo sapiens programmed cell death 1 ligand 1(PD-L1/CD274), transcript variant 1, residue 19-239aa, with C-terminal DDK/His tag, expressed in HEK293 cells. 20 ug
$900.00
TP700201 Purified recombinant protein of Homo sapiens programmed cell death 1 ligand 1 (PD-L1/CD274), residues 19-239aa, with C-terminal Fc tag, expressed in HEK293 cells. 20 ug
$900.00
TP710226 Purified recombinant protein of Human CD274 molecule (CD274), residues 19-290aa, with C-terminal DDK tag, expressed in sf9 insect cells 20 ug
$540.00
TP710227 Purified recombinant protein of Homo sapiens programmed cell death 1 ligand 1(PD-L1/CD274), transcript variant 1, extracellular domain residue (19-238aa) with C-terminal DDK tag, expressed and secreted from insect sf9 cells, 20ug 20 ug
$540.00
TP720630 Purified recombinant protein of Human PD-L1 / CD274 molecule (PD-L1 / CD274) 10 ug
$175.00
TP721254 Human PD-L1 Protein (C-His) 25 ug
$300.00
TP721255 Human PD-L1 Protein (C-His-Avi) 25 ug
$300.00
TP721256 Biotinylated Human PD-L1 Protein (C-His-Avi) 25 ug
$430.00
TP721257 PE Conjugated Human PD-L1 Protein (C-His) 25 ug
$430.00
TP721258 APC Conjugated Human PD-L1 Protein (C-His) 25 ug
$430.00
TP721259 Human PD-L1 Protein (C-Fc) 25 ug
$300.00
TP721260 Human PD-L1 Protein (C-Fc-Avi) 25 ug
$300.00
TP721261 Biotinylated Human PD-L1 Protein (C-Fc-Avi) 25 ug
$430.00
TP721262 PE Conjugated Human PD-L1 Protein (C-Fc) 25 ug
$430.00
TP721263 APC Conjugated Human PD-L1 Protein (C-Fc) 25 ug
$430.00
TP723946 Recombinant human PD-L1 protein with C-terminal mouse Fc and 6×His tag 100 ug
$905.00
TP762432 Purified recombinant protein of Human PD-L1 / CD274 molecule (PD-L1 / CD274), Trp13-Thr239, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$240.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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