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PD-L1 (CD274) Mouse Monoclonal Antibody [Clone ID: OTI2C7]

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SKU
TA507087
PD-L1 / CD274 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
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LY415473 Transient overexpression lysate of PD-L1 / CD274 molecule (PD-L1 / CD274) (as WB positive control) 100 ug
$436.00

View other "PD-L1 or NM_014143" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2C7
Application FC, IF, IHC, LMNX, WB
Recommended Dilution WB 1:200~2000, IF 1:100
Reactivity Human (Does not react with: Mouse)
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD274(NP_054862) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 31 kDa
Gene Name CD274 molecule
Database Link
Synonyms B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1
Reference Data
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Cytokines, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
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Other "OTI2C7" antibodies (4)
SKU Description Size Price
CF507087 Carrier-free (BSA/glycerol-free) CD274 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7) 100 ug
$620.00
TA507087AM PD-L1 / CD274 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7), Biotinylated 100 ul
$509.00
TA507087BM PD-L1 / CD274 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7), HRP conjugated 100 ul
$509.00
TA507087S PD-L1 / CD274 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7) 30 ul
$200.00

file-alt Citations

RNF138 promotes cisplatin resistance and PD-L1-mediated immune evasion via JAK2/STAT3 activation in nasopharyngeal carcinoma
He, Lou, Lei et al
Cell Rep (2026) 45 (6), 117547 DOI: 10.1016/j.celrep.2026.117547
AI Summary: In this study, the OriGene PD-L1 antibody (Cat# TA507087S; RRID:AB_2624079) was used to assess PD-L1 expression, helping to elucidate the role of RNF138 in promoting immune evasion in nasopharyngeal carcinoma.
Snippet: RNF138 Abclonal Cat# A10304;RRID:AB_2757847 PD-L1 CELNOVTE Cat# CSP1062-1.0 PD-L1 Origene Cat# TA507087S;RRID:AB_2624079 CD3 ZSGB-BIO Cat# ZM-0417;RRID:AB_2890105
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma
Liang, He, Liu et al
Biochim Biophys Acta Mol Cell Res (2024) 1871 (7), 119781 DOI: 10.1016/j.bbamcr.2024.119781
Cited by 21
AI Summary: In this study, the OriGene anti-PD-L1 antibody (TA507087) was used to detect PD-L1 protein levels, contributing to the investigation of the relationship between vimentin and PD-L1 in esophageal squamous cell carcinoma.
Snippet: was blocked with 5 % BSA/TBST buffer for 1.5 h at room temperature and incubated with anti-β-actin, anti-vimentin (ab62194;dilution at 1:1000;Abcam), and anti-PD-L1 (TA507087;dilution at 1:2000;Origene, USA) antibodies diluted in TBST buffer overnight at 4 °C. Then, the membranes were incubated with horseradish peroxidase (HRP)-conjugated anti-mouse or anti-rabbit IgG (bs-0295G-AP;Bioss, China)
WB
PD-L1 detection on circulating tumor-derived extracellular vesicles (T-EVs) from patients with lung cancer
Wu, Gu, Kang et al
Transl Lung Cancer Res (2021) 10 (6), 2441-2451 DOI: 10.21037/tlcr-20-1277
Cited by 40
AI Summary: In this study, OriGene products—specifically the A549 (Cat# CL-0016) and SK-MES1 (Cat# CL-0007) lung cancer cell lines—were used as sources of tumor-derived exosomes to validate the newly developed Simoa Epcam-PD-L1 extracellular vesicle detection assay.
FigureFigureFigure
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma
Du, Gao, Zhao et al
Oncol Lett (2018) 15 (6), 9317-9326 DOI: 10.3892/ol.2018.8530
Cited by 26
AI Summary: In this study, OriGene’s ALK (TA808063) and PD-L1 (TA591004) antibodies were used for immunohistochemical analysis to detect ALK and PD-L1 expression in tumor cells, aiding in the diagnosis and characterization of epithelioid inflammatory myofibroblastic sarcoma.
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma
Du, Gao, Zhao et al
Oncol Lett (2018)
AI Summary: OriGene products contributed to this paper by providing the primary antibodies for ALK (TA801287) and PD-L1 (TA507087), which were used in immunohistochemical analyses to characterize the tumor.
Snippet: Table I. Primary antibodies used for immunohistochemistry. Target Supplier Catalog number Dilution Staining ALK Origene Technologies, Inc., Beijing, China TA801287 Ready to use + PD‑L1 Origene Technologies, Inc. TA507087 Ready to use +
Showing 1-5 of 5 papers.
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