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MCSF Receptor (CSF1R) Human Recombinant Protein

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SKU
TP723975
Recombinant human CSF1R protein with C-terminal 6×His tag
Size:
100 ug
  $770.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA300025 MCSF Receptor (CSF1R) Antibody (C-term)
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Other products for "MCSF Receptor"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CSF1R(Ile20-Leu514) 6×His tag
Tag C-6×His Tag
Predicted MW The protein has a predicted molecular mass of 55.6 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 1436
UniProt ID P07333
Synonyms CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR
Summary The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Protein Categories Cancer: Gynecologic, CD Markers, Chemokines, Cytokines, Enzyme: Kinases, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Pathways in cancer
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Other "MCSF Receptor" proteins (6)
SKU Description Size Price
PH305288 CSF1R MS Standard C13 and N15-labeled recombinant protein (NP_005202) 10 ug
$3,360.00
LC401594 Lyophilized CSF1R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401594 Transient overexpression lysate of colony stimulating factor 1 receptor (CSF1R) (as WB positive control) 100 ug
$436.00
TP305288 Recombinant protein of human colony stimulating factor 1 receptor (CSF1R), 20 µg 20 ug
$737.00
TP700112 Purified recombinant protein of human colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R), with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00
TP710105 Recombinant protein of human colony stimulating factor 1 receptor (CSF1R), residues 20-517aa, with C-terminal DDK tag, expressed in sf9, 20ug 20 ug
$540.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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