IL6 Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 47.9 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA, Flow Cyt |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 3569 |
| UniProt ID | P05231 |
| Synonyms | IL6;Interleukin-6;BSF2;HSF;IFNB2 |
| Summary | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. |
| Protein Categories | Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | ELISA, Flow Cyt |
| Protein Pathways | Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IL6" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302078 | IL6 MS Standard C13 and N15-labeled recombinant protein (NP_000591) | 10 ug |
$3,360.00
|
|
| LC424617 | Lyophilized IL6 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424617 | Transient overexpression lysate of interleukin 6 (interferon, beta 2) (IL6) (as WB positive control) | 100 ug |
$436.00
|
|
| TP302078 | Recombinant protein of human interleukin 6 (interferon, beta 2) (IL6), 20 µg | 20 ug |
$867.00
|
|
| TP701114 | Purified recombinant protein of Human interleukin 6 (interferon, beta 2) (IL6), Val30-End, tag free, secretory expressed in HEK293 cells, 50ug | 50 ug |
$900.00
|
|
| TP720008 | Recombinant protein of human interleukin 6 (interferon, beta 2) (IL6), the mature form (Pro29-Met212) with C-terminal His tag | 10 ug |
$290.00
|
|
| TP723713 | Purified recombinant protein of Human interleukin 6 (interferon, beta 2) (IL6) | 10 ug |
$345.00
|
|
| TP750006 | Recombinant protein of human Interleukin 6(IL-6) produced in E. coli. | 50 ug |
$540.00
|
|
Citations
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