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B7H3 (CD276) Human Recombinant Protein

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SKU
TP723935
Recombinant human B7-H3 protein with C-terminal mouse Fc and 6×His tag
Size:
100 ug
  $795.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA813302 CD276 mouse monoclonal antibody, clone OTI1A10 100 ul
$447.00

Other products for "B7H3"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
B7-H3(Leu29-Pro245) mFc(Pro99-Lys330) 6×His
Tag C-Mouse Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 70-75 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 80381
UniProt ID Q5ZPR3
Synonyms B7-H3;CD276;B7 homolog 3
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Categories ADC Targets, CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families ELISA
Protein Pathways Cell adhesion molecules (CAMs)
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Other "B7H3" proteins (9)
SKU Description Size Price
PH315291 CD276 MS Standard C13 and N15-labeled recombinant protein (NP_079516) 10 ug
$3,360.00
LC410803 Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422539 Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC425464 Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410803 Transient overexpression lysate of CD276 molecule (CD276), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY422539 Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY425464 Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP315291 Recombinant protein of human CD276 molecule (CD276), transcript variant 2, 20 µg 20 ug
$737.00
TP700270 Purified recombinant protein of human CD276 molecule (CD276), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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