B7H3 (CD276) (NM_001024736) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-DDK/His |
| Predicted MW | 49 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | PBS, pH 7.4, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001019907 |
| Locus ID | 80381 |
| UniProt ID | Q5ZPR3 |
| Cytogenetics | 15q24.1 |
| RefSeq Size | 3419 |
| RefSeq ORF | 1602 |
| Synonyms | 4Ig-B7-H3; B7-H3; B7H3; B7RP-2 |
| Summary | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2011 |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "B7H3" proteins (9)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH315291 | CD276 MS Standard C13 and N15-labeled recombinant protein (NP_079516) | 10 ug |
$3,360.00
|
|
| LC410803 | Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422539 | Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC425464 | Lyophilized CD276 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY410803 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422539 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY425464 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP315291 | Recombinant protein of human CD276 molecule (CD276), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP723935 | Recombinant human B7-H3 protein with C-terminal mouse Fc and 6×His tag | 100 ug |
$795.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.