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MGMT (NM_002412) Human Recombinant Protein

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SKU
TP721020
Purified recombinant protein of Human O-6-methylguanine-DNA methyltransferase (MGMT)
Size:
10 ug 500 ug 50 ug 1 mg
  $260.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met1-Asn207
Tag N-His
Predicted MW 23.8 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mMTris-HCl, 1mM EDTA, pH 8.0 .
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002403
Locus ID 4255
UniProt ID P16455
Cytogenetics 10q26.3
RefSeq Size 866
RefSeq ORF 621
Summary Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. provided by RefSeq, Sep 2015
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "MGMT" proteins (4)
SKU Description Size Price
LC432155 Lyophilized MGMT HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY432155 Transient overexpression lysate of O-6-methylguanine-DNA methyltransferase (MGMT) (as WB positive control) 100 ug
$436.00
TP329131 Recombinant protein of human O-6-methylguanine-DNA methyltransferase (MGMT), 20 µg 20 ug
$737.00
TP760054 Recombinant protein of human O-6-methylguanine-DNA methyltransferase (MGMT), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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