NCALD (NM_001040624) Human Recombinant Protein

CAT#: TP720212

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Recombinant protein of human neurocalcin delta (NCALD), transcript variant 1

  View other "NCALD" proteins (32)

USD 300.00

2 Weeks

    • 10 ug

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Product Data
Description Recombinant protein of human neurocalcin delta (NCALD), transcript variant 1
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC221428, encoding the polypeptide (Gly2-Phe193) of human NCALD
Tag C-His
Predicted MW 24.4 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 40% Glycerol, pH 8.0.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at -80°C.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_001035714
Locus ID 83988
Refseq Size 3760
Cytogenetics 8q22.3
Refseq ORF 579
Synonyms MGC33870; MGC74858
Summary This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]


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