ROR2 (NM_004560) Human Recombinant Protein

SKU
TP710168
Purified protein of Human receptor tyrosine kinase-like orphan receptor 2 (ROR2), residues 34-403aa, with C-terminal DDK tag, expressed in sf9, 20ug
$515.00
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Specifications
Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, [RC215640], encoding the region(Met-Glu34-Gly403) of Homo sapiens ROR2
Tag C-DDK
Predicted MW 41.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004551
Locus ID 4920
UniProt ID Q01974
Cytogenetics 9q22.31
RefSeq Size 4091
RefSeq ORF 2829
Synonyms BDB; BDB1; NTRKR2
Summary The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase, Transmembrane
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Citations

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