CD30 (TNFRSF8) (NM_001243) Human Recombinant Protein

CAT#: TP710113

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Recombinant protein of human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, residues 19-379aa, with C-terminal DDK tag,expressed in sf9 cells


Product Datasheet for 'TP710113'


  View other "TNFRSF8" proteins (4)

USD 425.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, residues 19-379aa, with C-terminal DDK tag,expressed in sf9 cells
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC219819, encoding the region(Met-Phe19-Lys379) of Homo sapiens TNFRSF8
Tag C-DDK
Predicted MW 40.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001234
Locus ID 943
Refseq Size 3686
Cytogenetics 1p36.22
Refseq ORF 1785
Synonyms CD30; D1S166E; Ki-1
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction

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