CD30 (TNFRSF8) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide. The apparent molecular mass of CD30-His is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 943 |
| UniProt ID | P28908 |
| Synonyms | TNFRSF8;CD30;D1S166E;Ki-1 |
| Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "CD30" proteins (10)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH319819 | TNFRSF8 MS Standard C13 and N15-labeled recombinant protein (NP_001234) | 10 ug |
$3,360.00
|
|
| LC420050 | Lyophilized TNFRSF8 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY420050 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| TP319819 | Recombinant protein of human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP710113 | Recombinant protein of human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, residues 19-379aa, with C-terminal DDK tag,expressed in sf9 cells | 20 ug |
$540.00
|
|
| TP721319 | Human CD30/TNFRSF8 Protein (C-His) | 25 ug |
$300.00
|
|
| TP721320 | Human CD30/TNFRSF8 Protein (C-His-Avi) | 25 ug |
$300.00
|
|
| TP721321 | Biotinylated Human CD30/TNFRSF8 Protein (C-His-Avi) | 25 ug |
$430.00
|
|
| TP721322 | PE Conjugated Human CD30/TNFRSF8 Protein (C-His) | 25 ug |
$430.00
|
|
| TP721323 | APC Conjugated Human CD30/TNFRSF8 Protein (C-His) | 25 ug |
$430.00
|
|
Citations
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