CTBP2 (NM_001329) Human Recombinant Protein
Recombinant protein of human C-terminal binding protein 2 (CTBP2), transcript variant 1
Specifications
Product Data | |
Description | Recombinant protein of human C-terminal binding protein 2 (CTBP2), transcript variant 1 |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC224861. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 48.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001320 |
Locus ID | 1488 |
Refseq Size | 2368 |
Cytogenetics | 10q26.13 |
Refseq ORF | 1335 |
Synonyms | C-terminal binding protein 2; OTTHUMP00000020699; OTTHUMP00000020701; ribeye |
Summary | This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014] |
Protein Families | Stem cell - Pluripotency, Stem cell relevant signaling - Wnt Signaling pathway |
Protein Pathways | Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
Citations (2)
The use of this Proteins has been cited in the following citations: |
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Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
,Di Magno, L;Manni, S;Di Pastena, F;Coni, S;Macone, A;Cairoli, S;Sambucci, M;Infante, P;Moretti, M;Petroni, M;Nicoletti, C;Capalbo, C;De Smaele, E;Di Marcotullio, L;Giannini, G;Battistini, L;Goffredo, BM;Iorio, E;Agostinelli, E;Maroder, M;Canettieri, G;,
Cell Rep 2020
,PubMed ID 32049007
[CTBP2]
|
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes
,Boxer, LD;Barajas, B;Tao, S;Zhang, J;Khavari, PA;,
Genes Dev. Sep 2014
,PubMed ID 25228645
[CTBP2]
|
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
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LC420003 | CTBP2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 170.00 |
|
LC421253 | CTBP2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 170.00 |
|
LY420003 | Transient overexpression lysate of C-terminal binding protein 2 (CTBP2), transcript variant 1 |
USD 550.00 |
|
LY421253 | Transient overexpression lysate of C-terminal binding protein 2 (CTBP2), transcript variant 3 |
USD 550.00 |
|
PH313339 | CTBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001077383) |
USD 2,260.00 |
|
PH324861 | CTBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001320) |
USD 2,260.00 |
|
TP313339 | Recombinant protein of human C-terminal binding protein 2 (CTBP2), transcript variant 3 |
USD 788.00 |
USD 350.00
USD 379.00