BPGM (NM_001724) Human Recombinant Protein

CAT#: TP323838

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Recombinant protein of human 2,3-bisphosphoglycerate mutase (BPGM), transcript variant 1


 Product Datasheet for 'TP323838'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human 2,3-bisphosphoglycerate mutase (BPGM), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 29.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001715
Locus ID 669
Refseq Size 1800
Cytogenetics 7q33
Refseq ORF 777
Synonyms DPGM; ECYT8
Summary 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Protein Families Druggable Genome
Protein Pathways Glycolysis / Gluconeogenesis, Metabolic pathways

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