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IL5RA (NM_175727) Human Recombinant Protein

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SKU
TP322553
Purified recombinant protein of Homo sapiens interleukin 5 receptor, alpha (IL5RA), transcript variant 5, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC222553 representing NM_175727
Red=Cloning site Green=Tags(s)

MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKIN
APKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTE
DNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDW
LAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTR
NGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 37.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_783854
Locus ID 3568
UniProt ID Q01344
Cytogenetics 3p26.2
RefSeq Size 1956
RefSeq ORF 999
Synonyms CD125; CDw125; HSIL5R3; IL5R
Summary The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. provided by RefSeq, Jul 2011
Protein Categories CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
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Other "IL5RA" proteins (12)
SKU Description Size Price
PH305386 IL5RA MS Standard C13 and N15-labeled recombinant protein (NP_783852) 10 ug
$3,360.00
PH322553 IL5RA MS Standard C13 and N15-labeled recombinant protein (NP_783854) 10 ug
$3,360.00
LC403576 Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC406266 Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC406268 Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC424642 Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403576 Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 6 (as WB positive control) 100 ug
$436.00
LY406266 Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY406268 Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 5 (as WB positive control) 100 ug
$436.00
LY424642 Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP305386 Recombinant protein of human interleukin 5 receptor, alpha (IL5RA), transcript variant 3, 20 µg 20 ug
$737.00
TP723993 Recombinant human L5RA protein with C-terminal 6×His tag 100 ug
$770.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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