IL5RA (NM_175727) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC222553 |
| Predicted MW | 37.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_783854 |
| RefSeq Size | 1956 |
| RefSeq ORF | 999 |
| Synonyms | CD125; CDw125; HSIL5R3; IL5R |
| Locus ID | 3568 |
| UniProt ID | Q01344 |
| Cytogenetics | 3p26.2 |
| Summary | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. provided by RefSeq, Jul 2011 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IL5RA" proteins (12)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305386 | IL5RA MS Standard C13 and N15-labeled recombinant protein (NP_783852) | 10 ug |
$3,360.00
|
|
| LC403576 | Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406266 | Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406268 | Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424642 | Lyophilized IL5RA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403576 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 6 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406266 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406268 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 5 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424642 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| TP305386 | Recombinant protein of human interleukin 5 receptor, alpha (IL5RA), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
| TP322553 | Purified recombinant protein of Homo sapiens interleukin 5 receptor, alpha (IL5RA), transcript variant 5, 20 µg | 20 ug |
$737.00
|
|
| TP723993 | Recombinant human L5RA protein with C-terminal 6×His tag | 100 ug |
$770.00
|
|
Citations
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