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CYLD (NM_015247) Human Recombinant Protein

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SKU
TP319629
Recombinant protein of human cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
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Frequently Bought Together (2)

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100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC219629 protein sequence
Blue=ORF Red=Cloning site Green=Tag(s)

MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRI
PSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLS
KGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGV
YQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV
GETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHIN
DIIPALSESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNG
SSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLP
FSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE
NPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCR
PDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNS
CYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIM
KLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFME
KNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDL
LEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSL
PKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNG
FNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 107.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_056062
Locus ID 1540
UniProt ID Q9NQC7
Cytogenetics 16q12.1
RefSeq Size 5371
RefSeq ORF 2868
Synonyms BRSS; CDMT; CYLD1; CYLDI; EAC; FTDALS8; MFT; MFT1; SBS; TEM; USPL2
Summary This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Peptidases, Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways RIG-I-like receptor signaling pathway
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Documents
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Other "CYLD" proteins (9)
SKU Description Size Price
PH304099 CYLD MS Standard C13 and N15-labeled recombinant protein (NP_001035814) 10 ug
$3,360.00
PH314451 CYLD MS Standard C13 and N15-labeled recombinant protein (NP_001035877) 10 ug
$3,360.00
PH319629 CYLD MS Standard C13 and N15-labeled recombinant protein (NP_056062) 10 ug
$3,360.00
LC420845 Lyophilized CYLD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420886 Lyophilized CYLD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY420845 Transient overexpression lysate of cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY420886 Transient overexpression lysate of cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 3 (as WB positive control) 100 ug
$665.00
TP304099 Recombinant protein of human cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 2, 20 µg 20 ug
$737.00
TP314451 Recombinant protein of human cylindromatosis (turban tumor syndrome) (CYLD), transcript variant 3, 20 µg 20 ug
$737.00

file-alt Citations

CYLD-TRAF6 interaction promotes ADP-heptose-induced NF-κB signaling in H. pylori infection
Lim, Maubach, Naumann
EMBO Rep (2025)
Cited by 5
AI Summary: OriGene’s recombinant human CYLD protein (SKUTP319629) was used in this study to investigate the role of CYLD in promoting ADP-heptose-induced NF-κB signaling during H. pylori infection.
Snippet: Recombinant human A20 protein BPS Bioscience 80408 Recombinant human CYLD protein OriGene SKUTP319629 Recombinant human TIFA protein Novus Biologicals NBP1-99103-50ug Recombinant human TRAF6 protein US Biological 375664 Recombinant human IL-1β PeproTech
Showing 1-1 of 1 papers.
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