UBE3A (NM_000462) Human Recombinant Protein
SKU
TP316727
Recombinant protein of human ubiquitin protein ligase E3A (UBE3A), transcript variant 2, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 100.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000453 |
| Locus ID | 7337 |
| UniProt ID | Q05086 |
| Cytogenetics | 15q11.2 |
| RefSeq Size | 4516 |
| RefSeq ORF | 2625 |
| Synonyms | ANCR; AS; E6-AP; EPVE6AP; HPVE6A |
| Summary | This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. provided by RefSeq, Jul 2008 |
| Protein Categories | Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "UBE3A" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH313039 | UBE3A MS Standard C13 and N15-labeled recombinant protein (NP_570854) | 10 ug |
$3,360.00
|
|
| PH316727 | UBE3A MS Standard C13 and N15-labeled recombinant protein (NP_000453) | 10 ug |
$3,360.00
|
|
| LC400164 | Lyophilized UBE3A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408892 | Lyophilized UBE3A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400164 | Transient overexpression lysate of ubiquitin protein ligase E3A (UBE3A), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408892 | Transient overexpression lysate of ubiquitin protein ligase E3A (UBE3A), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP313039 | Purified recombinant protein of Homo sapiens ubiquitin protein ligase E3A (UBE3A), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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