UBE3A (NM_130839) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC213039 |
| Predicted MW | 100.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_570854 |
| RefSeq Size | 5211 |
| RefSeq ORF | 2616 |
| Synonyms | ANCR; AS; E6-AP; EPVE6AP; HPVE6A |
| Locus ID | 7337 |
| UniProt ID | Q05086 |
| Cytogenetics | 15q11.2 |
| Summary | This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "UBE3A" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH316727 | UBE3A MS Standard C13 and N15-labeled recombinant protein (NP_000453) | 10 ug |
$3,360.00
|
|
| LC400164 | Lyophilized UBE3A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408892 | Lyophilized UBE3A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400164 | Transient overexpression lysate of ubiquitin protein ligase E3A (UBE3A), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408892 | Transient overexpression lysate of ubiquitin protein ligase E3A (UBE3A), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP313039 | Purified recombinant protein of Homo sapiens ubiquitin protein ligase E3A (UBE3A), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
| TP316727 | Recombinant protein of human ubiquitin protein ligase E3A (UBE3A), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
