NCALD (NM_001040626) Human Recombinant Protein

CAT#: TP314160

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Purified recombinant protein of Homo sapiens neurocalcin delta (NCALD), transcript variant 3


 Product Datasheet for 'TP314160'

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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Homo sapiens neurocalcin delta (NCALD), transcript variant 3
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 22.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001035716
Locus ID 83988
Refseq Size 3673
Cytogenetics 8q22.3
Refseq ORF 579
Synonyms MGC33870; MGC74858
Summary This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

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