NCALD (NM_001040626) Human Recombinant Protein

CAT#: TP314160

Purified recombinant protein of Homo sapiens neurocalcin delta (NCALD), transcript variant 3

Product images

Specifications

Product Data

• Description: Purified recombinant protein of Homo sapiens neurocalcin delta (NCALD), transcript variant 3
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 22.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_001035716
• Locus ID: 83988
• Refseq Size: 3673
• Cytogenetics: 8q22.3
• Refseq ORF: 579
• Synonyms: MGC33870; MGC74858
• Summary: This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]