GLUT4 (SLC2A4) (NM_001042) Human Recombinant Protein

CAT#: TP313717

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Recombinant protein of human solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4)


 Product Datasheet for 'TP313717'

  View other "SLC2A4" proteins (3)

USD 748.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 54.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001033
Locus ID 6517
Refseq Size 2128
Cytogenetics 17p13.1
Refseq ORF 1527
Synonyms GLUT4
Summary This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Adipocytokine signaling pathway, Insulin signaling pathway, Type II diabetes mellitus

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Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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