PPM1B (NM_002706) Human Recombinant Protein
SKU
TP312918
Recombinant protein of human protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 52.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002697 |
| Locus ID | 5495 |
| UniProt ID | O75688 |
| Cytogenetics | 2p21 |
| RefSeq Size | 2605 |
| RefSeq ORF | 1437 |
| Synonyms | PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX |
| Summary | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase, Stem cell - Pluripotency |
| Protein Pathways | MAPK signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PPM1B" proteins (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH309425 | PPM1B MS Standard C13 and N15-labeled recombinant protein (NP_808908) | 10 ug |
$3,360.00
|
|
| PH312918 | PPM1B MS Standard C13 and N15-labeled recombinant protein (NP_002697) | 10 ug |
$3,360.00
|
|
| PH322782 | PPM1B MS Standard C13 and N15-labeled recombinant protein (NP_808907) | 10 ug |
$3,360.00
|
|
| LC406063 | Lyophilized PPM1B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC419156 | Lyophilized PPM1B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422387 | Lyophilized PPM1B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY406063 | Transient overexpression lysate of protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY419156 | Transient overexpression lysate of protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY422387 | Transient overexpression lysate of protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| TP309425 | Recombinant protein of human protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
| TP322782 | Recombinant protein of human protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
Selective peroxynitrite-mediated protein nitration catalyzed by glyoxalase domain containing protein 4
Wright, Dang, Hussain et al
Proc Natl Acad Sci U S A (2026) 123 (6), e2515002123 DOI: 10.1073/pnas.2515002123
Wright, Dang, Hussain et al
Proc Natl Acad Sci U S A (2026) 123 (6), e2515002123 DOI: 10.1073/pnas.2515002123
Cited by 3
AI Summary: OriGene products PPM1b (#TP312918), PQBP1 (#TP323943), and HAGHL (#RC200832) were used as recombinant protein substrates to assess glyoxalase domain-containing protein 4 (GLOD4)-mediated selective protein nitration in this study.
Snippet: … Other putative substrates, i.e., β-syn (rPeptide #S-1003), PPM1b (Origene #TP312918), PQBP1 (Origene #TP323943), OXCT1 (CDI Labs #JHU13084.B15C7R12), AIFM2 (CDI Labs #JHU14077.B10C28R38), and CAPR1N1 (CDI Labs #JHU12559.B10C28R16), were similarly tested. Nitration d;- #TP306860), MBLAC2 (LS Bio#LS-G73730), and HAGHL (OriGene #RC200832) was determined by incubating each protein with 100 μM peroxynitrite (50 μM for HAGHL)
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
