IKBKE (NM_014002) Human Recombinant Protein
SKU
TP312481
Recombinant protein of human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE), 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 80.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_054721 |
| Locus ID | 9641 |
| UniProt ID | Q14164 |
| Cytogenetics | 1q32.1 |
| RefSeq Size | 3263 |
| RefSeq ORF | 2148 |
| Synonyms | IKK-E; IKK-i; IKKE; IKKI |
| Summary | IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 PubMed 19481526).supplied by OMIM, Oct 2009 |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IKBKE" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH312481 | IKBKE MS Standard C13 and N15-labeled recombinant protein (NP_054721) | 10 ug |
$3,360.00
|
|
| LC415533 | Lyophilized IKBKE HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415533 | Transient overexpression lysate of inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE) (as WB positive control) | 100 ug |
$665.00
|
|
Citations
SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection
Espada, Sari, Cahill et al
J Biol Chem (2023) 299 (7), 104925 DOI: 10.1016/j.jbc.2023.104925
Espada, Sari, Cahill et al
J Biol Chem (2023) 299 (7), 104925 DOI: 10.1016/j.jbc.2023.104925
Cited by 14
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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